The agouti-related protein and body fatness in humans

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Leptin and its neuronal targets, which produce proopiomelanocortin (POMC) and agouti-related protein (AgRP), regulate energy balance. This study characterized leptin, POMC, and AgRP in the cerebrospinal fluid (CSF) of 47 healthy human subjects, 23 lean and 24 overweight/obese (OW/OB), as related to BMI, adiposity, plasma leptin, soluble leptin receptor (s-OB-R), and insulin. POMC was measured s...

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ژورنال

عنوان ژورنال: International Journal of Obesity

سال: 2003

ISSN: 0307-0565

DOI: 10.1038/sj.ijo.802201